Vetmedin side effects include difficulty breathing, swelling of the lips,face or tounge. sudden onset of diarrhea, vomiting, shock, seizures, pale gums, coma. Continue giving Vetmedin and contact your veterinarian if your pet develops; poor appetite, drowsiness, diarrhea, labored breathing, weakness, incoordination, fainting, accumulation of fluid in the lungs or abdomen, and cough. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to the pet.